Author

Yi-Qing Zheng

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Sep 2026

Development of a subunit vaccine candidate (RBD-HA trimer) provides dual protection against multi-subtype avian influenza viruses and QX-type infectious bronchitis virus.

A chimeric subunit vaccine, RBD-HA, in which the receptor-binding domain of the QX-type IBV spike protein replaced the immunodominant head domain of H9N2 AIV haemagglutinin is developed, providing proof of concept for a bivalent subunit vaccine targeting two major avian respiratory viruses.

Yi-Qing Zheng, Bing-Chen Qiao, Zi-He Gao et al. · Vaccine · 0 citations

Sep 2026

Transcriptome screening identifies circRNA-INSR as a novel host factor associated with avian influenza virus replication.

This study is the first to identify circ-INSR as a host factor contributing to influenza virus replication, and provides a basis for developing circRNA-based strategies against H9N2 avian influenza virus.

Zhi-Yuan Liu, Meng-Lu Fan, Yi-Qing Zheng et al. · Virology · 0 citations

Open access Jul 2026

LncRNA ckATP1A1-AS1 inhibits influenza A virus replication by mediating innate immune responses and suppressing viral nuclear import

These findings establish ckATP1A1-AS1 as a key antiviral lncRNA that restricts IAV replication by coordinating innate immune signaling and directly targeting several steps in the viral replication cycle.

Meng-Lu Fan, Zhi-Yuan Liu, Lu-Lu Deng et al. · Journal of Virology · 0 citations