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Review Open access Oct 2026

Natural killer cells in colorectal cancer liver metastasis: redefining immune surveillance and plasticity

Natural killer (NK) cells are key effectors in innate immunity and serve as early responders against disseminated tumor cells. In colorectal cancer liver metastasis (CRLM), the liver’s unique immune landscape presents both challenges and opportunities for NK cell–mediated tumor control. While NK cells have long been co...

Yi Lu, Chen-Yue Xia, Jin-Hui Gu · 0 citations
Review Open access Aug 2026

Clonal Hematopoiesis in Colorectal Cancer: Mechanisms and Implications

Clonal hematopoiesis (CH) arises from the expansion of hematopoietic stem and progenitor cells bearing somatic mutations, often in genes linked to epigenetic regulation and inflammation. Once considered a benign age‐related phenomenon, CH has gained increasing attention for its potential to influence cancer biology bey...

Chenyue Xia, Yi Lu, Jinhui Gu · 1 citation

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