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Review Open access Sep 2026

Circulating Cell-free DNA as a biomarker for radiation-induced injury: From mechanistic insights to clinical translation

This review summarizes the mechanisms linking radiation injury to cfDNA release, current detection technologies, and evidence for organ-specific applications and discusses clinical confounders, translational barriers, and future directions for integrating cfDNA into precision radiation oncology.

Qi-Xin Sun, Yi-Kun Li, Tian-Wen Yin et al. · 0 citations

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