Sep 2026
The Delivery Strategies for PROTAC.
Yi-Jing Dang, Ze-Li Long, Jing Gao et al.
· Handbook of Experimental Pha... · 0 citations
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Sep 2026
Molecular design and delivery of extracellular and membrane protein degradation chimeras.
Extracellular and membrane-associated proteins constitute a substantial therapeutic target space that remains largely inaccessible to intracellular degradation strategies based on the ubiquitin-proteasome system. Membrane and extracellular targeted protein degradation (meTPD) addresses this limitation by coupling targe...
Shu-Tong Lin, Hui-Ling Zhou, Jia-Yan Qiu et al.
· Advanced Drug Delivery Revie... · 0 citations
Jul 2026
Molecular Engineering of Stimuli-Activatable Protein Degraders for Precise Cancer Therapy.
This Account systematically summarizes recent advances regarding the rational design of stimuli-activatable protein degraders, and strategically outline the "when and how" of integrating these degraders with nanomedicine platforms to tailor precise cancer therapy.
Jing Gao, Yi Lai, Bo Hou et al.
· Accounts of Chemical Researc... · 0 citations