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Yi-Hang Xiao

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Open access Oct 2026

Compositional Brain Age Profiles Reveal Disease-Related Neuroimaging Patterns Beyond the Brain Age Gap

The brain age gap (BAG)—the difference between the predicted and chronological age—does not describe the imaging patterns underlying such deviation. To characterize these patterns, we developed a semantic-guided mixture-of-experts model using multimodal imaging-derived phenotypes and their metadata. Global and local ex...

Wei Wang, Yi-Hang Xiao, Jia-Jie Peng · 0 citations

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