Yi-Han Zhang

BANF1 at the crossroads of genome stability and innate immunity: emerging implications for hematologic malignancies

Genomic instability and immune escape are linked features of hematologic malignancies, but the mechanisms that allow malignant cells to tolerate persistent nuclear and genotoxic stress while avoiding damaging DNA-sensing responses remain incompletely defined. Barrier-to-autointegration factor 1 (BANF1) is a small DNA-b...