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Author

Yi-Fei Zhang

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Review Open access Sep 2026

Research progress on the pathophysiological mechanisms of pioglitazone-induced heart failure: a review

While fluid retention and vascular changes demonstrate strong clinical evidence, direct myocardial toxicity remains primarily observed in vitro and lacks clinical confirmation, whereas evidence for genetic susceptibility and direct cardiotoxicity remains limited.

Jian-Li Li, Yi-Fei Zhang, Xue-Wen Li · 0 citations
Open access Sep 2026

Genetic Evidence for a Putative B Cell–Cholate Immunometabolic Axis in Pericarditis: A Mendelian Randomization Study

Background: Pericarditis is an inflammatory heart disease with unclear causal mechanisms. Immune dysregulation is implicated, but observational studies cannot reliably infer causality. Whether plasma metabolites mediate immune-pericarditis pathways remains unknown. Methods: A two-sample Mendelian randomization (MR) stu...

Yi-Fei Zhang, Wu-Xiao Yang, Xue-Wen Li · 0 citations

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