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Author

Yi-Fang Jiang

2 papers indexed here

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Oct 2026

Oxysophocarpine attenuates acute liver injury by targeting FBP1 to suppress ferroptosis and enhance cellular resilience via the PPARα-GPX4 axis.

Acute liver injury (ALI) is a life-threatening clinical condition with limited therapeutic options. Through network pharmacology screening, we identified oxysophocarpine (OSC), a natural compound derived from traditional Chinese medicine, as a potent reactive oxygen species-scavenging agent. In LPS/D-GalN-induced ALI m...

Jin-Jin Shi, Yan-Jun Liu, Ran Wang et al. · 0 citations
Open access Sep 2026

Nifuroxazide Pretreatment Protects Against Acute CdCl2 Exposure-Induced Toxicity via Modulating the USP21/AIM2 Inflammasome Axis

Cadmium (Cd) is a ubiquitous environmental pollutant with an exceptionally long biological half-life (10–30 years) and high multi-organ toxicity. While chronic cadmium exposure has been extensively studied, the pathological mechanisms and prophylactic strategies for acute cadmium poisoning remain poorly defined. Here,...

Jing Yu, Feng Xu, Ran Wang et al. · 0 citations

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