Open access
Aug 2026
Preliminary Exploration on Melatonin-Mediated Protective Effects in Intracranial Aneurysms: Transcriptomic, Proteomic, and Metabolomic Profiling of Cerebral Vascular Tissues Combined with in vivo Animal Experiments
Integrated transcriptomic and proteomic analyses suggest that Npy may be a key molecule in regulating IA progression and mediating MLT therapeutic effects, and its potential value is further supported by the immunohistochemical validation results.
Yan Liu, Hao-Yue Jiang, Yi-Fan Lu et al.
· Drug Design, Development and... · 0 citations