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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Yi Cui

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Review Sep 2026

Abstract B033: Integrating spatial biology and peripheral blood biomarkers to map treatment resistance in pancreatic ductal adenocarcinoma

Despite recent advances in RAS-directed therapy, pancreatic ductal adenocarcinoma (PDAC) remains highly lethal. Surgical resection, chemotherapy, and radiotherapy continue to anchor treatment, but therapeutic resistance is pervasive, and most patients succumb to treatment-refractory residual disease. Advances in sing...

D. Olgun, Beatrice Awasthi, N. Lester et al. · 0 citations
Open access Aug 2026

Plaque-associated oligodendrocyte proteostatic failure underlies myelin loss in Alzheimer’s disease

Findings identify plaque-associated oligodendrocyte proteostatic failure as a candidate mechanism of myelin loss and a potential therapeutic pathway in AD and restores MBP protein levels and improves compact myelin ultrastructure in AD organoids.

Jong Shin, Nandita Joshi, Brendan F. Miller et al. · 0 citations

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