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Open access Sep 2026

Development of a Recombinant O/CATHAY Topotype Foot-and-Mouth Disease Virus as a Resource for Vaccine Matching and Efficacy Evaluation

Foot-and-mouth disease virus serotype O remains a global threat, particularly the O/CATHAY topotype in East and Southeast Asia. Because timely access to emerging field isolates can be limited, reverse genetics provides a flexible approach for generating viruses representing selected circulating strains for vaccine matc...

Yerin Kim, Y. Chae, Yoon-Hee Lee et al. · 0 citations
Open access Sep 2026

Functional Evaluation of Neutralizing Antibodies Against Foot-and-Mouth Disease Virus Serotype O Using a Luciferase-Based Surrogate Neutralization Assay

The feasibility of the surrogate neutralization assay for assessing the functional activity of neutralizing antibodies and its potential applicability to vaccine immunogenicity assessment and functional antibody analysis is demonstrated.

Hyejin Kim, Dong-Wan Kim, Y. Chae et al. · 0 citations

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