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Author

Ye Yi

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Open access Sep 2026

TP53 Loss Elevates NF‐κB‐IFN‐β‐MHC‐Ia Signaling to Promote NK Cell Resistance in Osteosarcoma

ABSTRACT TP53 inactivation is a key event in osteosarcoma (OS) development and underlies its aggressiveness, yet its role in tumor‐immune interactions remains poorly understood. Here, we investigate how p53 loss alters osteosarcoma susceptibility to natural killer (NK) cell‐mediated cytotoxicity using OS cell lines and...

Gui-Hui Qin, Cheung-Kwan Yeung, Ye Yi et al. · 0 citations
Open access Sep 2026

Human-Mouse Chimerism for Organogenesis Without Neural or Germline Contributions

Human pluripotent cells, including embryonic stem cells (ESCs), have been used for interspecies blastocyst complementation, with the potential to generate human organs in animals for clinical applications. However, ethical concerns exist as human cells may contribute to the germline and central nervous system (CNS) in...

Sen Ye, Kailibinuer Kadier, Ye Yi et al. · 0 citations

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