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Author

Ye-Qing Du

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2 papers indexed here

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Oct 2026

A Radical Addition–Diradical Coupling Switch Unifies Cytochrome P450-Catalyzed Diketopiperazine Dimerization

Cytochrome P450 dimerases generate the remarkable structural diversity of dimeric diketopiperazine (DKP) natural products through highly selective intermolecular radical-mediated reactions. Although radical addition mechanisms have been established for most bacterial DKP dimerization modes, the molecular basis underl...

Ye-Qing Du, Tai-Ping Zhou, Wen-Ya Tian et al. · 0 citations
Open access Sep 2026

Structural and Mechanistic Basis of Dual Substrate Promiscuity in the Acyltransferase AntB Enables Late-Stage Diversification of Natural Products.

This study systematically characterize AntB and uncover its remarkable dual substrate promiscuity, and establishes AntB as a versatile biocatalyst for late-stage natural product diversification.

Meng-Meng Zheng, Yu-Han Dai, Xiang-Yu Li et al. · 0 citations

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