Discovery of Novel Dual-Functional Phenylthiazole-Benzamide Hybrids as Succinate Dehydrogenase-Inhibiting Fungicides with Promising Phloem Mobility
To discover novel phloem-mobile succinate dehydrogenase inhibitor (SDHI) fungicides, 36 phenylthiazole derivatives incorporating amide fragments were designed, synthesized, and evaluated for their antifungal activity. Compound G3 exhibited the highest in vitro activity against Sclerotinia sclerotiorum (EC50 = 0.614 μ...