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Yaxin Wu

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Open access Dec 2025

DeepAden: an explainable machine learning method for predicting the substrate specificity of nonribosomal peptide synthetases

DeepAden achieves competitive performance compared with state-of-the-art tools on a benchmark dataset, and enabled the identification of two Streptomyces NRPS gene clusters through accurate A-domain substrates specificity predictions.

Jiaquan Huang, Liangjun Ge, Yaxin Wu et al. · bioRxiv · 0 citations