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Author

Yasunari Kanda

2 papers indexed here

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Sep 2026

Beyond NAMs versus animal models: Context of use as the governing framework for integrated nonclinical strategies in drug development.

New approach methodologies (NAMs) originated in chemical hazard assessment, where two forces operate together: the scale of characterizing many substances, and a long-standing ethical and legal commitment to replacing animal testing. Drug development is weighted differently. It is a translational and decision problem a...

Stefano Gaburro, B. Berridge, Nicholas W. Kelley et al. · 0 citations
Review Sep 2026

[Global trends in drug development using alternatives to animal testing].

This review outlines international and domestic regulatory trends in NAMs and highlights recent advances in organ-specific toxicity assessment using human-relevant models, including cardiotoxicity, hepatotoxicity, and neurotoxicity.

S. Yanagida, Hiroyuki Kawagishi, Yasunari Kanda · 0 citations

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