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Yasuhiro Watanabe

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7-Ketocholesterol induces ROS-mediated mRNA expression of 12-lipoxygenase, cyclooxygenase-2 and pro-inflammatory cytokines in human mesangial cells: Potential role in diabetic nephropathy

A C T 7-Ketocholesterol (7-KCHO) is a highly proinflammatory oxysterol and plays an important role in the pathophysiology of diabetic nephropathy (DN).Lipoxygenases (LOXs) and cyclooxygenases (COXs) are also involved in the development of DN.The aim of this study was to clarify the effects of 7-KCHO on mRNA expression...

Yasuhiro Watanabe · 0 citations

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