Author

Yasuhiko Ago

2 papers indexed here

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Review Open access Sep 2026

Emerging NPR-B agonists for cartilage and bone: from CNP biology to translational compound design

Disorders affecting cartilage and bone development frequently originate from disrupted endochondral ossification within growth-plate cartilage. Nonetheless, few therapeutic interventions directly target the local signaling pathways governing this process. This review explores the C-type natriuretic peptide (CNP)/natr...

Yasuhiko Ago, A. Karunathilaka, Jacky M. Guerrero-Vargas et al. · Frontiers in Chemistry · 0 citations

Open access Aug 2026

Comprehensive characterization and translational implications of the GalnsR384C mouse model of Mucopolysaccharidosis IVA.

GalnsR384C and GalnsR384Y mice recapitulate key biochemical, skeletal, and histopathological features of MPS IVA and provide well-characterized murine models of severe GALNS loss-of-function resulting from clinically relevant missense variants.

Dione A Holder, B. Çelik, Sampurna Saikia et al. · Journal of Human Genetics · 0 citations