Open access
Oct 2026
Preparation of Extracellular Matrices and Cell/Matrix Functional Units Produced by Cultured and Primary Fibroblasts.
Fibroblast-derived matrices (FDMs) provide a biologically relevant in vitro alternative to conventional two-dimensional (2D) substrates by enabling fibroblasts to assemble and organize their own extracellular matrix (ECM) environment, closely mimicking the physiological stromal microenvironment. This unit describes met...
Aleksandr Dolskii, J. Franco-Barraza, Mariia Dmitrieva et al.
· Current Protocols · 0 citations