Author

Yasemin van Heuvel

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Open access Jul 2026

High Cell Density Cultivation of HEK293 Cells Using a 2L Membrane-Stirred Bioreactor.

A novel membrane-stirrer (MemStir) based bioreactor that employs multiple hollow-fiber membrane sheets arranged in a device that facilitates efficient gas transfer through bubble-free diffusion for HCD cultivations is investigated, suggesting that the MemStir system is a viable option for HCD cultivation because it can...

Lennart Jacobtorweihe, Yasemin van Heuvel, Kathrina Scheiermann et al. · Biotechnology and Bioenginee... · 0 citations

Open access Aug 2026

High-titer human packaging cells producing γ-retroviral vectors pseudotyped with engineered baboon endogenous retrovirus (BaEV) envelope proteins

This proof-of-concept study underlines the utility of the Env variant BaEV-TR for the establishment of stable pseudotype VPCLs and the utilization of HT1080 cells as an alternative to frequently used 293T host cells.

Angelina Hallik, Mona Pißarreck, Mats Jürgen Grummel et al. · Frontiers in Molecular Medic... · 0 citations