Author

Yao Lu

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Open access Sep 2026

MOD-scTWAS: Leveraging gene co-expression for single-cell transcriptome-wide association studies

Transcriptome-wide association studies (TWAS) provide an effective framework for identifying genes associated with complex traits. Population-scale single-cell transcriptomic data enable genetically regulated expression (GReX) prediction and TWAS analyses at cell-type resolution, but the predictive performance of exist...

Han-Min Guo, Yao Lu, Lin Hou · bioRxiv · 0 citations