Author

Yao Huang

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Open access Sep 2026

Hydroxytyrosol Restrains NLRP3 Inflammasome Activation and Pyroptosis Through the TLR4/NF-κB Pathway to Prevent Mycoplasma gallisepticum-Inflammation.

Mycoplasma gallisepticum (MG), a significant pathogen, causes chronic respiratory disease (CRD) in poultry, characterized by coughing, wheezing, and dyspnea. This widespread disease severely impedes the healthy development of the poultry industry. Hydroxytyrosol (HT), a plant-derived monomeric compound, possesses diver...

Shun-Xing Liu, Yan-Ling Xiong, Zhen-Tao Cheng et al. · Poultry Science · 0 citations

Open access Sep 2026

AGE-RAGE/NF-κB/SIRT3 signaling cascade is implicated in mitochondrial dysfunction in diabetic gastroparesis

Diabetic gastroparesis is a severe complication of diabetes mellitus, yet its underlying molecular mechanisms remain poorly understood. This study investigated how advanced glycation end products (AGEs) trigger mitochondrial dysfunction through NF-κB activation and SIRT3 suppression in diabetic gastroparesis. We anal...

Peng Zhang, Yao Huang, Ya-Ping Yang et al. · Scientific Reports · 0 citations

Review Open access Jul 2026

Targeting mitochondrial dysfunction with traditional Chinese medicine for inflammatory bowel disease: a comprehensive review

Current research on how active metabolites of TCM modulate mitochondrial dysfunction in the prevention and treatment of IBD is summarized, providing new insights into the pathogenesis of the disease and opening up new avenues and strategies for the prevention, treatment, and research on IBD treatment with TCM.

Linxi Zeng, Yao Huang, Jiayi Ke et al. · Frontiers in Pharmacology · 0 citations