Author

Yani Zhang

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Open access Jul 2026

Integrated metabolomic and transcriptomic analyses reveal that glutamine promotes chicken primordial germ cell-like cell specification potentially through α-ketoglutarate

Glutamine promotes the specification of chicken PGCLC and correlates with alterations in cellular metabolism and increased H3K4me2 levels during differentiation, providing new insights into the metabolic basis of PGC formation and a foundation for improving PGC culture and expansion in poultry.

Qing-Qing Geng, Lei Zhang, Zhe Wang et al. · Animal bioscience · 0 citations

Review Open access Jul 2026

Clustered regularly interspaced short palindromic repeats‑associated protein 9 (CRISPR-Cas9) based genome editing in avian primordial germ cells: Comparative technologies, translational applications, and regulatory challenges

This review critically evaluates genome-editing tools in avian PGCs, including CRISPR/Cas9, transcription activator-like effector nucleases (TALENs), base editing, and prime editing, and their applications.

Mazhar Farooq, Dayong Han, Lei Zhang et al. · Poultry Science · 0 citations