Open access
Jul 2026
Efficient chemical reprogramming of human T cells into functional megakaryocytes and platelets
This work established a robust method that successfully generated induced MKs (iMKs) from human cord blood–derived CD3+ T cells, which is a more abundant source and highlighted an optimized chemical reprogramming strategy that enables efficient conversion of T cells to MKs.
Jinhua Qin, Zheng Hua, Xingxing Zhao et al.
· Science Advances · 0 citations