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Yangguang Su

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Open access Oct 2026

Construction of a GCSCs-Related Prognostic Risk Model Based on Transcriptomic Data

Gastric Cancer Stem Cells (GCSCs) contribute to tumor progression and treatment resistance, but their heterogeneity and tumor microenvironment interactions remain unclear. We analyzed GSE163558 single-cell RNA-sequencing data from 10 gastric cancer samples and integrated GCSC-related genes with The Cancer Genome Atlas...

Xin Hu, Shi-Qi Fan, Nai-Qiang Liu et al. · 0 citations
Open access Jul 2026

Deciphering the Leading-Edge Spatiotemporal Microenvironment of Hepatocellular Carcinoma for Targeted Drug Discovery Using SpaPred

SpaPred provides a hypothesis-generating framework for investigating spatial heterogeneity and candidate therapeutic vulnerabilities in HCC and prioritized Oxaliplatin, Belinostat, and Temsirolimus as candidate compounds associated with LE-related transcriptional programs.

Shi-Bo Zhang, Ziqiao Li, Kexin Yu et al. · 0 citations

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