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Sep 2026

Anti-inflammatory limonoids from Swietenia macrophylla seeds attenuate IL-1β release via NLRP3 inflammasome inhibition.

Seeds of Swietenia macrophylla are recognized as a beneficial dietary supplement due to their pronounced hypoglycemic and hypotensive properties. To explore the pharmaceutical potential of this plant, eight previously undescribed mexicanolide- and phragmalin-type limonoids (1-8), together with twenty known analogues (9...

Yun-Peng Sun, Zhe Xie, Wan-Bai Su et al. · 0 citations
Aug 2026

Carboxamide derivatives isolated from the endophytic fungus Diaporthe phaseolorum associated with Polygonatum cyrtonema Hua.

From the endophytic fungus Diaporthe phaseolorum associated with Polygonatum cyrtonema Hua, nine carboxamides were isolated, comprising five new compounds, phaseolorines A-E (1-3a, 4a, 6), along with four known compounds (3b, 5, 7, 8). Compounds 1-3 feature a rare 3-imidazolinozone structural unit, previously reported...

Huai-Qing Xu, Si-rui Wang, Xiaomeng Hou et al. · 0 citations

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