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Yang-Yang Hu

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Open access Oct 2026

Gut Microbiota-Derived Short-Chain Fatty Acids Mediate the Bone-Protective Effects of Metformin Against Postmenopausal Osteoporosis.

BACKGROUND Dysbiosis-induced inflammation has been implicated in postmenopausal osteoporosis (PMOP). Although metformin has shown benefits for bone health, the exact role of the gut microbiota in the mechanism underlying this relationship remains unclear. HYPOTHESIS/PURPOSE We hypothesised that metformin could allevi...

Zeng-Lin Tan, Jing-Jing Zeng, Fu-Rong Huang et al. · 0 citations

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