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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Yang Yang

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2 papers indexed here

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Open access Oct 2026

Infection of macrophages by mpox virus activates inflammasome and cell death, informing multitarget therapeutic strategies.

Severe mpox virus (MPXV) infection causes immunopathological manifestations in patients. Here, we provide clinical evidence of MPXV-induced inflammation in a large patient cohort and demonstrate direct macrophage infection in skin tissues from an autopsied mpox patient. In human macrophages, MPXV efficiently enters, re...

Yi-Ning Wang, Xin Wang, T. Tsikari et al. · 0 citations
Open access Sep 2026

Discovery of the nucleoside analogue FMAU as a broad-spectrum anti-orthopoxvirus inhibitor in vitro and in vivo using a structure-guided hit expansion strategy

In vivo mouse studies showed that FMAU treatment provided full protection against lethal VACV and MPXV challenges, while significantly reducing viral loads in lung tissues, and oral FMAU administration retained potent therapeutic efficacy against MPXV in a mouse model of MPXV infection.

Ting-Ting Zheng, Yong Feng, Chang Xu et al. · 0 citations

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