Author

Yang Xie

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Open access Aug 2026

NanoPrism: A Taxonomy-Guided Pipeline for Rapid Functional Profiling of Oxford Nanopore Long-Read Metagenomes

NanoPrism offers a computationally efficient option for taxonomy-guided functional profiling of bacterial isolates and defined microbial communities and offers validation on complex clinical and environmental metagenomes, broader forms of taxonomic-classification error, and dedicated fungal benchmarks remain necessary.

Jiwoong Kim, Shuheng Gan, Harish Jawahar et al. · DNA · 0 citations

Open access Jul 2026

Spatial Topology Reveals Biologically Distinct Recurrent Motifs in Colorectal Cancer

STORM provides an annotation-free framework for discovering recurrent spatial motifs and identifies a fibroblast barrier architecture whose topological association with immune exclusion is independent of effector abundance, amplified in early-onset disease, and translatable to a deployable pathology-based prognostic bi...

Jia Yao, Yuqiu Yang, Yi Jiang et al. · bioRxiv · 0 citations