Mapping the complement-targeted landscape in igA nephropathy: a systematic review with structured descriptive synthesis
Background Complement activation is a key driver of disease progression in IgA nephropathy (IgAN). While previous syntheses were limited to phase II evidence, pivotal phase III data—including the 24-month results of the APPLAUSE-IgAN trial—have recently emerged, necessitating an updated appraisal of complement-targeted...
Xin-Yu Li, Chang-Ying Zhong, Li-Nan Zhang et al.
· Frontiers in Medicine · 0 citations