Phenotypic heterogeneity and genetic mechanisms of phage resistance in hypervirulent carbapenem-resistant Klebsiella pneumoniae
Four distinct resistance phenotypes in K2-serotype hypervirulent carbapenem-resistant Klebsiella pneumoniae under the selective pressure of phage Kpph1 are identified, suggesting multifaceted resistance strategies, including receptor masking, growth inhibition, and community-level resistance.