A target-cell-oriented pharmacological map that integrates their autophagic targets, ferroptotic effects, disease contexts and relevant target-cell populations is constructed, thereby providing a rationale for developing ADF-based therapeutic strategies with defined indications, measurable pharmacodynamic biomarkers an...
Xiao Cui, Xinzhu Dong, Yang Li et al.· Pharmacological Research· 0 citations
This review systematically summarizes the molecular mechanisms underlying LMP initiation and execution, as well as the regulatory pathways of LDCD modalities, including apoptosis, necroptosis, ferroptosis, pyroptosis, immunogenic cell death, and autophagy-dependent death.
Yang Li, Jiajie Feng, Xinzhu Dong et al.· Biomarker Research· 1 citation
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