Open access
Sep 2026
Realgar Transforming Solution Triggers Ferroptosis-Associated Death in NB4 Leukemia Cells through Disruption of Iron Homeostasis and Suppression of the SLC7A11/GPX4 Axis.
It is indicated that RTS induces ferroptosis-associated cell death in NB4 cells by disrupting iron homeostasis and inhibiting the SLC7A11/GPX4 axis, supporting further investigation of RTS as a modernized arsenic-based anti-leukemic formulation.
Zhao-Rong Yue, Qing-Hong Liu, Yan-Ni Wang et al.
· Biological and Pharmaceutica... · 0 citations