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Oct 2026

Gestational exposure to per- and polyfluoroalkyl substances drives maternal liver dysfunction through lipid dysregulation and NF-κB/EGFR-STAT3 inflammatory activation.

Per- and polyfluoroalkyl substances (PFAS) are ubiquitous persistent pollutants in pregnant women, yet mechanisms of PFAS-triggered gestational liver injury remain poorly understood. This work quantified 18 serum PFAS in 221 pregnant participants and explored PFAS-liver function associations via epidemiological analyse...

Shu-Han Li, Yang Li, Yi-Wen Wang et al. · 0 citations
Open access Oct 2026

Placental Transfer of PFAS and Their Sex-Specific Associations With Neonatal Thyroid Hormones in a Chinese Birth Cohort.

Perfluoroalkyl and polyfluoroalkyl substances (PFAS) are persistent environmental endocrine-disrupting chemicals that can cross the placental barrier and may disrupt fetal thyroid homeostasis; however, the sex-specific thyroid toxicity of PFAS remains poorly characterized. This study recruited 247 mother-infant pairs f...

Shu-Han Li, Yang Li, Xing-Jin Liao et al. · 0 citations

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