Yang-Kun Shen

Innate immunity-mediated inflammation and immunopathogenesis in HSV-1-infected encephalitis.

HSV-1 encephalitis (HSE) remains a devastating viral infection of the central nervous system despite effective antiviral therapy. Increasing evidence indicates that disease outcome is not determined by viral replication alone but by how innate immunity is calibrated within the brain. Studies of host susceptibility in c...