Yang-Gang Hong

Unveiling the molecular bridge between hearing loss and dementia via plasma proteomic mapping.

BackgroundHearing loss (HL) is a potentially modifiable risk factor for dementia, but the circulating molecular features shared by hearing impairment and dementia remain unclear.ObjectiveTo derive a plasma proteomic signature of hearing impairment and examine its association with incident all-cause dementia and its sta...

Dissecting immune-psychiatric links: a Mendelian randomization analysis of antibody-mediated responses and mental health disorders.

Plasma metabolomic signatures of migraine in 479,760 adults

Large-scale prospective evidence is provided supporting a structured plasma metabolomic profile associated with hospital-diagnosed migraine and contextualize systemic lipid and lipoprotein metabolism as a relevant domain for future mechanistic and translational studies of migraine-related metabolic variation.

Joint Effects of Adverse Childhood Experiences and Genetic Burden of Depression on Multiple Depressive Symptoms.

Both ACEs and genetic burden of depression are associated with an increased risk of depressive symptoms, and their joint effects significantly increase the risk of all types of depressive symptoms.