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Author

Yang Chen

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Open access Sep 2026

Distinct molecular profiles of indeterminate and malignant thyroid nodules in patients under 21 years of age

The RET/NTRK/ALK-positive <21-year group demonstrated enrichment of angiogenesis and EMT pathways, higher ERK/EMT/FMT scores, and lower BRS/TDS vs genotyped-matched adults, providing mechanistic insight into the more invasive phenotype in pediatric and young adult TNs.

J. Ricarte-Filho, L. Castellanos, Steven G. Waguespack et al. · 0 citations

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