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Open access Aug 2026

Perilipin 2 drives cisplatin-induced acute kidney injury in young but not aged kidneys

Cisplatin is a widely used chemotherapeutic agent, but acute kidney injury (AKI) remains its dose-limiting toxicity, particularly in older patients. In recent years, dysregulated lipid metabolism has emerged as a key driver of cisplatin nephrotoxicity; however, the underlying mechanisms and their modulation across ages...

Saiya Zhu, Chen Dai, Kelly Zheng et al. · 0 citations
Open access Jul 2026

Toward simple, rapid, and deep plant proteome analysis with an in-cell proteomics strategy

Abstract While liquid chromatography-mass spectrometry (LCMS) has revolutionized plant proteomics over the past decade, plant sample preparation remains a major challenge due to rigid cell walls, abundant secondary metabolites, and wide dynamic range of protein abundance. These hurdles demand laborious tissue disruptio...

Deji Adekanye, Jasmine Parks, Meghana Kusuru et al. · 0 citations

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