Open access
Sep 2026
A Sequential Assembly Mechanism for Stable Cdc13 Dimerization on Telomeric DNA
The telomere-binding protein Cdc13 specifically binds to single-stranded telomeric DNA, playing a critical role in telomere protection and length regulation. While extensive biochemical, molecular biological, and genetic studies have shown that Cdc13 can form dimers or oligomers in solution and bind telomeric DNA with...
Po-Wei Chiu, Yu-Ting Lin, Pei-Ru Lai et al.
· bioRxiv · 0 citations