Functional involvement of HMGB1-related neuroinflammation in depression and its modulation by intermittent theta-burst stimulation(iTBS).
PURPOSE Intermittent theta-burst stimulation (iTBS) is widely used for its rapid antidepressant efficacy in clinical practice. However, its underlying neuroimmune mechanisms and objective biomarkers of treatment response remain largely unexplored. High mobility group box 1 (HMGB1), a critical driver of neuroimmune inte...