The precise resolution of single-molecule events is often limited by the stochastic thermal motion of analytes, which traverse nanoscale sensing zones too rapidly for conventional detection bandwidths. This remains a fundamental challenge in nanopore chemistry, particularly for small and flexible peptides. Here, we r...
Yi-Heng Liu, Shi-Jun Lin, Ming-Lun Li et al.· Journal of the American Chem...· 0 citations
The para-substituted luminophore is further developed into a β-galactosidase-activatable probe, enabling real-time, longitudinal imaging of DOX-induced senescent tumor in vivo and offers a versatile platform for biomarker-activatable sonoafterglow imaging.
Shuai-Ge Bai, Ming-Hui Wang, Zheng-Kang Cheng et al.· Journal of the American Chem...· 0 citations
A tumor-specific RANP for precision molecular imaging that activates its radioafterglow signal specifically in the presence of hydrogen peroxide, a key biomarker of the tumor microenvironment is developed.