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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

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Yan-Yu Zhang

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Review Open access Sep 2026

UBA1 as a proteostasis-innate immunity checkpoint: lessons from vexas syndrome and therapeutic implications

It is proposed that UBA1 functions as a proteostasis-innate immunity checkpoint whose biological output is determined by residual enzymatic activity, subcellular distribution, lineage context, and clone size and suggests a mechanism-based approach to therapeutic intervention in VEXAS syndrome and malignancy.

Yan-Yu Zhang, Quan-Xin Su · 0 citations

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