Review
Open access
Jul 2026
Protein lactylation in cancer: principles, programmes and therapeutic opportunities.
Lactylation is a recently identified metabolism-associated post-translational modification that provides a mechanistic link between tumor metabolic reprogramming and epigenetic regulation. Although aberrant lactate accumulation in tumor tissues has long been recognized, a comprehensive and unified understanding of how...
Xiaoyun Bu, Xinyue Yu, Jie Wang et al.
· Molecular Cancer · 1 citation