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Jul 2026

CST1 suppresses ferroptosis and restricts CD8+ T-cell infiltration and effector function in lung adenocarcinoma via activation of the WNT/β-catenin signaling pathway.

BACKGROUND Ferroptosis dysregulation and immune evasion are central features of lung adenocarcinoma (LUAD) progression, yet the molecular mechanisms that coordinately govern both processes remain poorly understood. This study aimed to identify ferroptosis-associated genes in LUAD and characterize their functional and m...

Zhuqing Ji, Yan Wang, Zhongneng Xu et al. · 0 citations

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