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Yan-Shuang Wu

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Open access Sep 2026

Daxx depletion remodels silent rDNA chromatin and increases UBF-bound transcriptional potential.

Ribosomal DNA (rDNA) repeats are regulated by DNA methylation, histone modifications, nucleosome occupancy, and nucleolar organization. Here, we used a data-driven ChIP-seq background-subtraction strategy to re-examine epigenetic profiles at rDNA repeats and found that Daxx and Atrx are preferentially enriched in the p...

Yan-Shuang Wu, Jing-Yi Xu, Xing-Wei Huang et al. · 0 citations

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