Author

Yan-Mei Li

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Review Open access Aug 2026

Artificial intelligence in rheumatoid arthritis: current applications and future perspectives

Rheumatoid arthritis (RA) is a highly prevalent systemic autoimmune disease characterized by a complex and partially understood pathogenesis. The substantial challenges in early identification and marked therapeutic heterogeneity pose a significant burden on affected patients. Despite notable advancements in diagnostic...

Zhan-Hui Sun, Cheng-Zhang Li, Kai-Rui Zhu et al. · Frontiers in Medicine · 0 citations

Review Open access Jul 2026

Immunological heterogeneity in rheumatoid arthritis: challenges in early-stage stratification, non-response to targeted therapy, and the restoration of immune tolerance

This review critically examines the mechanisms underlying RA immunological heterogeneity, including genetic susceptibility, epigenetic regulation, autoantibody diversification, synovial pathotypes, and gut-joint axis-related immune-metabolic interactions and highlights how a more critical understanding of RA heterogene...

Yan-Mei Li, Kai-Rui Zhu, Yushan Ding et al. · Frontiers in Immunology · 0 citations