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Open access Oct 2026

The pro-obesity role of G3BP1 through altering adipogenic differentiation in mice via the PI3K/AKT pathway

ABSTRACT As a growing but non-infectious epidemic, obesity is a common cause of several comorbidities. GTPase-activating protein SH3 domain-binding protein 1 (G3BP1) is a central regulator of stress‑granule assembly that has significant implications in metabolic disorders. This article aims to explore the functional me...

Hai-Yan Wang, Li-Tong Sun, Hai-Dan Mao et al. · 0 citations
Open access Sep 2026

Dual-Activating Pyroptosis and cGAS-STING Pathway for Immuno-Photodynamic Therapy Based on a Thermally Activated Delayed Fluorescence Photosensitizer.

Both in vitro and in vivo studies demonstrate that TA2O effectively eradicates tumor cells, promotes dendritic cell maturation, facilitates cytotoxic T lymphocyte infiltration, and induces a marked M2-to-M1 macrophage polarization, effectively promoting immune infiltration and inflammatory remodeling of the tumor micro...

Ru-Ming Jiang, Guo-Xi Yang, Jin-Ling Gu et al. · 0 citations

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