Background Immune checkpoint inhibitors (ICIs) can cause immune-related adverse events (irAEs) across multiple organs. High-throughput omics approaches may help characterize susceptibility, molecular mechanisms, diagnostic features, and monitoring markers related to irAEs; however, evidence remains dispersed across pla...
Jian-Fei Lu, Yan-Li Yang· Frontiers in Immunology· 0 citations
Inflammatory bowel disease (IBD) is a chronic, relapsing immune-mediated disorder of the gastrointestinal tract. Interstitial lung disease (ILD) associated with inflammatory bowel disease has been receiving increasing attention. With advances in the gut-lung axis theory, accumulating epidemiological and mechanistic evi...
Yan-Li Yang, Dong-Mei Zhang, Wen-Wen Liu· Frontiers in Cellular and In...· 0 citations
Toxic metal exposure is a pressing global health concern, with accumulating evidence linking it to the onset and progression of pulmonary fibrosis. Mechanistically, metal-induced pulmonary fibrosis operates through a complex, interconnected signaling network rather than a single linear cascade. The initiating role of o...