Author

Yan-Li Ni

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Open access Sep 2026

Mycn facilitates hematopoietic stem and progenitor cell generation from endothelial cells by inhibiting adhesion signaling.

It is demonstrated that endothelial-specific deletion of Mycn, but not Myc, impairs HSPC formation in mouse embryos and uncovers a regulatory mechanism whereby Mycn promotes HSPC generation from endothelial cells by suppressing adhesion signaling.

Chi Wang, Zhe Chen, Mei-Lin Jiang et al. · Cell Reports · 0 citations

Open access Sep 2026

Functional heterogeneity of mouse fetal liver hematopoietic stem cells revealed by clonal lineage tracing and single-cell transcriptomics.

A clonal-resolution view of fetal liver HSC heterogeneity is provided, enhancing the understanding of HSC diversity across different developmental stages and suggesting a specific coupling relationship between transcriptional persistence and lineage bias.

Man Zhang, Yan-Li Ni, Di Liu et al. · Zoological Research · 0 citations