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Author

Yan Li

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Aug 2026

Single-cell transcriptomic analysis reveals systemic immune dysregulation and identifies PLEK as a candidate hub gene associated with CD8+ T-cell activation in myasthenia gravis.

This study provides a systems-level view of immune dysregulation in MG, highlighting enhanced intercellular communication, T-cell dysregulation, and PLEK as a potential molecular marker associated with CD8+ T-cell activation and disease severity, offering insights into MG pathogenesis and therapeutic targets.

Jing-Nan Jin, Zi-Hong Chen, Yi-Ying Zhang et al. · 0 citations

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